ltaE protein (Legionella rubrilucens) - STRING interaction network

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second shell of interactors

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Predicted Interactions

gene neighborhood

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gene co-occurrence

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textmining

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protein homology

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Score

ltaE

Low specificity L-threonine aldolase. (342 aa)

Predicted Functional Partners:

Lrub_1741

0.800

ychF

0.720

glyA

0.719

Lrub_1743

0.714

Lrub_1740

0.702

ilvA

0.666

gcvT

0.656

gcsB

0.645

gcsA

0.641

cysK

0.623

Your Current Organism:

Legionella rubrilucens

NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lrub_1740	Lrub_1741	Lrub_1740	Lrub_1741	Transmembrane protein.	Putative aminoglycoside phosphotransferase.	0.702
Lrub_1740	Lrub_1743	Lrub_1740	Lrub_1743	Transmembrane protein.	Hypothetical protein.	0.618
Lrub_1740	ltaE	Lrub_1740	Lrub_1742	Transmembrane protein.	Low specificity L-threonine aldolase.	0.702
Lrub_1741	Lrub_1740	Lrub_1741	Lrub_1740	Putative aminoglycoside phosphotransferase.	Transmembrane protein.	0.702
Lrub_1741	Lrub_1743	Lrub_1741	Lrub_1743	Putative aminoglycoside phosphotransferase.	Hypothetical protein.	0.732
Lrub_1741	ltaE	Lrub_1741	Lrub_1742	Putative aminoglycoside phosphotransferase.	Low specificity L-threonine aldolase.	0.800
Lrub_1743	Lrub_1740	Lrub_1743	Lrub_1740	Hypothetical protein.	Transmembrane protein.	0.618
Lrub_1743	Lrub_1741	Lrub_1743	Lrub_1741	Hypothetical protein.	Putative aminoglycoside phosphotransferase.	0.732
Lrub_1743	ltaE	Lrub_1743	Lrub_1742	Hypothetical protein.	Low specificity L-threonine aldolase.	0.714
cysK	glyA	Lrub_2566	Lrub_1071	Cystathionine beta synthase.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.697
cysK	ilvA	Lrub_2566	Lrub_0495	Cystathionine beta synthase.	L-threonine dehydratase biosynthetic IlvA.	0.767
cysK	ltaE	Lrub_2566	Lrub_1742	Cystathionine beta synthase.	Low specificity L-threonine aldolase.	0.623
gcsA	gcsB	Lrub_2815	Lrub_2813	Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.	Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.	0.999
gcsA	gcvT	Lrub_2815	Lrub_2817	Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.	Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.	0.999
gcsA	glyA	Lrub_2815	Lrub_1071	Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.833
gcsA	ltaE	Lrub_2815	Lrub_1742	Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.	Low specificity L-threonine aldolase.	0.641
gcsB	gcsA	Lrub_2813	Lrub_2815	Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.	Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.	0.999
gcsB	gcvT	Lrub_2813	Lrub_2817	Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.	Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.	0.999
gcsB	glyA	Lrub_2813	Lrub_1071	Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.932
gcsB	ltaE	Lrub_2813	Lrub_1742	Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.	Low specificity L-threonine aldolase.	0.645