STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lrub_1762Mevalonate kinase. (293 aa)    
Predicted Functional Partners:
idi
Isopentenyl-diphosphate Delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
  
 
 0.943
Lrub_0271
Mevalonate diphosphate decarboxylase.
 
 
 0.918
mvaA_1
Hydroxymethylglutaryl CoA reductase; Belongs to the HMG-CoA reductase family.
 
 0.874
mvaA_2
Hydroxymethylglutaryl CoA reductase; Belongs to the HMG-CoA reductase family.
 
 0.873
fni
Isopentenyl pyrophosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.839
pksG
Polyketide biosynthesis 3-hydroxy-3-methylglutaryl-ACP synthase PksG.
 
 
 0.810
Lrub_1932
Cytosolic IMP-GMP specific 5'-nucleotidase.
  
     0.449
Lrub_1694
Cysteine protease.
  
     0.432
Lrub_0426
Hypothetical protein.
  
     0.410
Lrub_0968
Putative Smr domain protein.
  
  
  0.403
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
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