Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smc_4Chromosome partition protein Smc. (449 aa)    
Predicted Functional Partners:
Lrub_0166
Sensory box histidine kinase/response regulator.
 
 0.999
Lrub_0394
Sensor histidine kinase.
 0.999
Lrub_1872
Sensory box histidine kinase/response regulator.
 0.998
Lrub_0131
Regulatory protein (GGDEF and EAL domains).
  
 0.997
gacS/letS
Transmission sensor LetS.
 
 0.997
Lrub_1768
Inner membrane protein/sensory box protein LssE.
 
 0.995
fliN
Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
  
 0.993
Lrub_0189
GGDEF domain-containing sensory box protein.
 
 0.992
stuC_1
Sensor histidine kinase.
  
 0.992
Lrub_1459
Regulatory protein (GGDEF and EAL domains).
 
 0.992
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
Server load: low (40%) [HD]