pieE protein (Legionella rubrilucens) - STRING interaction network

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Score

pieE

Substrate of the Dot/Icm secretion system. (574 aa)

Predicted Functional Partners:

map

0.827

rpsN

0.827

dksA

0.738

rpmB

0.685

hisIE

0.660

hemD

0.568

Lrub_1927

0.542

rpmG

0.528

cobN

0.521

rpmE

0.453

Your Current Organism:

Legionella rubrilucens

NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lrub_1927	pieE	Lrub_1927	Lrub_1928	MAPEG family protein.	Substrate of the Dot/Icm secretion system.	0.542
cobN	hemD	Lrub_2319	Lrub_0355	Aerobic cobaltochelatase subunit CobN.	uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	0.803
cobN	pieE	Lrub_2319	Lrub_1928	Aerobic cobaltochelatase subunit CobN.	Substrate of the Dot/Icm secretion system.	0.521
dksA	hisIE	Lrub_2037	Lrub_0215	DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.	Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family.	0.598
dksA	pieE	Lrub_2037	Lrub_1928	DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.	Substrate of the Dot/Icm secretion system.	0.738
dksA	rpmE	Lrub_2037	Lrub_0416	DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.	50S ribosomal protein L31; Binds the 23S rRNA.	0.485
hemD	cobN	Lrub_0355	Lrub_2319	uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	Aerobic cobaltochelatase subunit CobN.	0.803
hemD	pieE	Lrub_0355	Lrub_1928	uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	Substrate of the Dot/Icm secretion system.	0.568
hisIE	dksA	Lrub_0215	Lrub_2037	Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family.	DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.	0.598
hisIE	map	Lrub_0215	Lrub_0253	Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family.	Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.	0.402
hisIE	pieE	Lrub_0215	Lrub_1928	Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family.	Substrate of the Dot/Icm secretion system.	0.660
hisIE	rpmE	Lrub_0215	Lrub_0416	Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family.	50S ribosomal protein L31; Binds the 23S rRNA.	0.671
map	hisIE	Lrub_0253	Lrub_0215	Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.	Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family.	0.402
map	pieE	Lrub_0253	Lrub_1928	Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.	Substrate of the Dot/Icm secretion system.	0.827
map	rpsN	Lrub_0253	Lrub_2496	Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.	30S ribosomal protein S14.	0.981
pieE	Lrub_1927	Lrub_1928	Lrub_1927	Substrate of the Dot/Icm secretion system.	MAPEG family protein.	0.542
pieE	cobN	Lrub_1928	Lrub_2319	Substrate of the Dot/Icm secretion system.	Aerobic cobaltochelatase subunit CobN.	0.521
pieE	dksA	Lrub_1928	Lrub_2037	Substrate of the Dot/Icm secretion system.	DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.	0.738
pieE	hemD	Lrub_1928	Lrub_0355	Substrate of the Dot/Icm secretion system.	uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	0.568
pieE	hisIE	Lrub_1928	Lrub_0215	Substrate of the Dot/Icm secretion system.	Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family.	0.660