Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lrub_20963-hydroxybutyrate dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (259 aa)    
Predicted Functional Partners:
adc
Acetoacetate decarboxylase; Catalyzes the conversion of acetoacetate to acetone and carbon dioxide; Belongs to the ADC family.
 
  
  0.991
Lrub_2095
Alpha-beta hydrolase family transporter esterase.
 
 
   0.950
mvaB
hydroxymethylglutaryl-CoA lyase.
   
 
  0.840
Lrub_1013
Acetoacetyl CoA synthetase.
     
  0.839
Lrub_0663
SAM-dependent O-methyltransferase.
 
  
   0.819
motA2
Flagellar motor protein MotA.
       0.750
motB_1
Flagellar motor protein MotB.
       0.738
Lrub_2097
Hypothetical protein.
       0.693
Lrub_0903
Patatin-like phospholipase.
 
 
   0.685
yueD
Sepiapterin reductase.
  
     0.629
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
Server load: medium (42%) [HD]