STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ypeAAcetyltransferase YpeA. (236 aa)    
Predicted Functional Partners:
Lrub_2356
Hypothetical protein.
       0.596
dlpA
DlpA protein (isocitrate and isopropylmalate dehydrogenase family protein).
       0.596
Lrub_2358
Hypothetical protein.
       0.596
Lrub_1848
Hypothetical protein.
   
   0.552
Lrub_2355
4-hydroxy-2-oxovalerate aldolase.
    
  0.500
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.444
Lrub_2354
UDP-N-acetylmuramyl tripeptide synthase.
       0.438
Lrub_2352
GNAT family acetyltransferase.
  
  
 0.418
Lrub_2351
Deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
       0.402
Lrub_2353
Methyltransferase.
       0.402
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.