Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pbpCPenicillin binding protein 1C. (769 aa)    
Predicted Functional Partners:
Lrub_2541
Hypothetical protein; Alpha-2-macroglobulin family N-terminal region.
   
 0.981
mrdA
Penicillin binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
  
  
 0.906
ftsI
Peptidoglycan synthetase FtsI precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
  
  
 0.893
ponA
Penicillin binding protein 1A.
  
  
0.878
dacB
D-alanyl-D-alanine carboxypeptidase.
   
 
 0.861
dacA
D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
     
 0.848
Lrub_2543
Hypothetical protein.
       0.572
Lrub_0328
D-alanyl-D-alanine carboxypeptidase.
     
  0.434
rodA
Rod shape-determining protein rodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
  
   
 0.426
Lrub_1552
N-acetylmuramoyl-L-alanine amidase.
     
  0.421
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.