STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lrub_2554Pteridine reductase. (247 aa)    
Predicted Functional Partners:
Lrub_2046
Phenylalanine-4-hydroxylase.
    
  0.840
folA
Dihydrofolate reductase FolA; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
     
 0.839
Lrub_2556
6-pyruvoyl tetrahydropterin synthase.
    
  0.797
Lrub_2555
Hypothetical protein.
       0.758
priA
Primosomal protein N' (replication factor Y); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
       0.758
ptlF
1-deoxy-11-beta-hydroxypentalenate dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
     0.712
yueD
Sepiapterin reductase.
  
     0.665
Lrub_0570
Short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
  0.615
Lrub_0793
Oxidoreductase, FAD-binding protein.
   
 0.614
fcbC
Thiesterase.
    
  0.582
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
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