STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
poxBPyruvate dehydrogenase; Belongs to the TPP enzyme family. (573 aa)    
Predicted Functional Partners:
edd
Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.
 
 
 0.816
Lrub_0064
Phosphate acetyl/butaryl transferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.810
Lrub_1766
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
  
 
 0.810
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
  
 
 0.808
pta_1
Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.
  
 0.795
pta_2
Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.
  
 0.795
dlpA
DlpA protein (isocitrate and isopropylmalate dehydrogenase family protein).
  
 0.783
Lrub_2355
4-hydroxy-2-oxovalerate aldolase.
  
 
 0.761
ilvA
L-threonine dehydratase biosynthetic IlvA.
  
 0.730
rpiA
Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
       0.715
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
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