STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
grlAGlutaredoxin-like protein; Belongs to the glutaredoxin family. Monothiol subfamily. (105 aa)    
Predicted Functional Partners:
Lrub_2111
Transcriptional regulator BolA; Belongs to the BolA/IbaG family.
 
 
 0.985
sufA
Fe-S cluster assembly protein; Belongs to the HesB/IscA family.
 
 0.821
erpA
Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG.
  
 0.781
djlA
DNA binding protein DnaJ, heat shock protein; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
     
 0.743
ahpC
Alkyl hydroperoxide reductase.
  
 
 0.715
Lrub_2585
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.659
Lrub_1233
BolA like protein; Belongs to the BolA/IbaG family.
 
 
 
 0.591
ubiH_2
2-polyprenyl-6-methoxyphenol hydroxylase.
  
     0.583
ubiH_1
2-octaprenyl-6-methoxyphenol hydroxylase.
  
     0.574
gshB
Glutathione synthetase; Belongs to the prokaryotic GSH synthase family.
  
     0.550
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
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