Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yraODnaA initiator-associating factor for replication initiation. (200 aa)    
Predicted Functional Partners:
Lrub_0999
D,D-heptose 1,7-bisphosphate phosphatase.
 
 
 0.977
Lrub_2655
Conserved hypothetical protein; putative periplasmic or secreted lipoprotein.
  
    0.911
Lrub_2654
Hemolysin, lipoprotein.
  
    0.906
hisB
Imidazole glycerol-phosphate dehydratase/histidinol phosphatase; In the N-terminal section; belongs to the histidinol- phosphatase family.
  
 
 0.872
Lrub_2657
Hypothetical protein; Belongs to the UPF0102 family.
  
    0.863
Lrub_2658
Lipoprotein.
  
    0.803
dnaA
Chromosome replication initiator DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
    
 
 0.796
kdsD
Polysialic acid capsule expression protein.
     
 0.756
rsmI
Tetrapyrrole (corrin/porphyrin) methylase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
       0.693
Lrub_0302
Heptosyl transferase, glycosyltransferase family 9 protein.
 
   
 0.690
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
Server load: medium (50%) [HD]