Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lrub_2661Metalloproteinase-like protein. (264 aa)    
Predicted Functional Partners:
Lrub_2662
Hypothetical protein.
       0.777
rsmI
Tetrapyrrole (corrin/porphyrin) methylase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
       0.692
ftsK
Cell division protein FtsK.
    
 
 0.660
Lrub_1932
Cytosolic IMP-GMP specific 5'-nucleotidase.
  
 
   0.654
Lrub_2660
Alkane monooxygenase.
       0.633
Lrub_0931
Serine metalloprotease; Belongs to the peptidase S8 family.
   
 0.624
lapB
Tetratricopeptide repeat protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.
    
 
 0.622
pepO
Metallopeptidase PepO, peptidase, M13 family.
 
    0.618
lasB
Virulence metalloprotease; Extracellular zinc metalloprotease.
 
 
 0.588
Lrub_1372
Hypothetical protein.
    
   0.584
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
Server load: low (12%) [HD]