Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
plaALysophospholipase A. (358 aa)    
Predicted Functional Partners:
Lrub_2686
Alpha helix protein; Belongs to the UPF0307 family.
       0.773
rlmL
Ribosomal RNA large subunit methyltransferase L; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family.
       0.773
lspD
Type II protein secretion LspD.
   
  
 0.724
lspI
Type II secretory pathway protein LspI.
      
 0.702
lspK
Type II secretory pathway protein LspK.
      
 0.702
lapB
Tetratricopeptide repeat protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.
      
 0.702
lspF
Type II secretory pathway protein LspF.
      
 0.667
Lrub_2684
Integral membrane protein.
       0.651
wrbA_2
Flavoprotein WrbA (Trp repressor binding protein).
       0.452
Lrub_2682
Pirin-like protein; Belongs to the pirin family.
       0.434
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
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