Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Lrub_2814YCII domain-containing protein. (102 aa)    
Predicted Functional Partners:
gcsB
Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily.
       0.870
gcsA
Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
       0.870
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
       0.870
gcvT
Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.
       0.799
Lrub_2812
Putative Diguanylate phosphodiesterase (EAL domain).
       0.728
Lrub_2822
Hypothetical protein.
       0.570
Lrub_2811
Hypothetical protein.
       0.450
hisIE
Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family.
  
    0.427
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
     
  0.415
Lrub_2818
Glyoxalase-like domain protein.
       0.408
Your Current Organism:
Legionella rubrilucens
NCBI taxonomy Id: 458
Other names: ATCC 35304, CCUG 29671, CIP 103848, DSM 11884, JCM 7565, L. rubrilucens, NCTC 11987, strain WA-270A-C2
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