| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lrub_2834 | Lrub_2836 | Lrub_2834 | Lrub_2836 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | Hypothetical protein. | 0.557 |
| Lrub_2834 | Lrub_2837 | Lrub_2834 | Lrub_2837 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | Oxidoreductase. | 0.452 |
| Lrub_2834 | acsB | Lrub_2834 | Lrub_2833 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.901 |
| Lrub_2834 | mmsA | Lrub_2834 | Lrub_2835 | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | Methylmalonate-semialdehyde dehydrogenase [acylating] (MMSDH), oxidoreductase. | 0.941 |
| Lrub_2836 | Lrub_2834 | Lrub_2836 | Lrub_2834 | Hypothetical protein. | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | 0.557 |
| Lrub_2836 | Lrub_2837 | Lrub_2836 | Lrub_2837 | Hypothetical protein. | Oxidoreductase. | 0.585 |
| Lrub_2836 | acsB | Lrub_2836 | Lrub_2833 | Hypothetical protein. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.584 |
| Lrub_2836 | mmsA | Lrub_2836 | Lrub_2835 | Hypothetical protein. | Methylmalonate-semialdehyde dehydrogenase [acylating] (MMSDH), oxidoreductase. | 0.688 |
| Lrub_2837 | Lrub_2834 | Lrub_2837 | Lrub_2834 | Oxidoreductase. | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | 0.452 |
| Lrub_2837 | Lrub_2836 | Lrub_2837 | Lrub_2836 | Oxidoreductase. | Hypothetical protein. | 0.585 |
| Lrub_2837 | acsB | Lrub_2837 | Lrub_2833 | Oxidoreductase. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.452 |
| Lrub_2837 | mmsA | Lrub_2837 | Lrub_2835 | Oxidoreductase. | Methylmalonate-semialdehyde dehydrogenase [acylating] (MMSDH), oxidoreductase. | 0.516 |
| acsB | Lrub_2834 | Lrub_2833 | Lrub_2834 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | 0.901 |
| acsB | Lrub_2836 | Lrub_2833 | Lrub_2836 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Hypothetical protein. | 0.584 |
| acsB | Lrub_2837 | Lrub_2833 | Lrub_2837 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Oxidoreductase. | 0.452 |
| acsB | mmsA | Lrub_2833 | Lrub_2835 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Methylmalonate-semialdehyde dehydrogenase [acylating] (MMSDH), oxidoreductase. | 0.888 |
| mmsA | Lrub_2834 | Lrub_2835 | Lrub_2834 | Methylmalonate-semialdehyde dehydrogenase [acylating] (MMSDH), oxidoreductase. | 3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. | 0.941 |
| mmsA | Lrub_2836 | Lrub_2835 | Lrub_2836 | Methylmalonate-semialdehyde dehydrogenase [acylating] (MMSDH), oxidoreductase. | Hypothetical protein. | 0.688 |
| mmsA | Lrub_2837 | Lrub_2835 | Lrub_2837 | Methylmalonate-semialdehyde dehydrogenase [acylating] (MMSDH), oxidoreductase. | Oxidoreductase. | 0.516 |
| mmsA | acsB | Lrub_2835 | Lrub_2833 | Methylmalonate-semialdehyde dehydrogenase [acylating] (MMSDH), oxidoreductase. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.888 |