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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCCL_0022Two-component sensor histidine kinase. (612 aa)    
Predicted Functional Partners:
MCCL_0021
DNA-binding response regulator.
 0.998
MCCL_0024
Conserved hypothetical protein; Similar to functionally unknown protein.
 
  
 0.941
MCCL_0023
Conserved hypothetical protein; Similar to functionally unknown protein.
 
  
 0.932
MCCL_0025
Metallo-beta-lactamase family protein YycJ.
  
  
 0.837
phoP
Alkaline phosphatase synthesis transcriptional regulatory protein.
 
 0.770
MCCL_1066
Response regulator ArlR homolog.
 
 0.734
MCCL_1138
Response regulator protein.
 
 0.723
MCCL_0088
Conserved hypothetical protein; Similar to two-component response regulator.
 
 0.662
MCCL_0280
Two-component response regulator.
 
 0.546
pbpA
Penicillin-binding protein 1.
  
   
 0.538
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
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