STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCCL_0087Conserved hypothetical protein; Similar to ABC transporter, permease protein. (340 aa)    
Predicted Functional Partners:
MCCL_0086
ABC transporter, ATP-binding protein homolog.
 
 0.991
MCCL_0311
Conserved hypothetical protein; Similar to functionally unknown protein.
  
 
 0.881
MCCL_0114
ABC transporter ATP-binding protein.
 
 
 0.860
MCCL_0421
Multidurg resistance protein A homolog.
  
  
 0.774
MCCL_0282
ABC transporter ATP-binding protein.
  
 
 0.745
MCCL_0089
Conserved hypothetical protein; Similar to two-component sensor kinase protein.
 
 
 
 0.744
MCCL_0088
Conserved hypothetical protein; Similar to two-component response regulator.
       0.565
pykA
Pyruvate kinase; Belongs to the pyruvate kinase family.
       0.454
MCCL_0113
Conserved hypothetical protein; Similar to ABC transporter permease.
 
  
0.436
topB
DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...]
     
 0.416
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.