STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCCL_0111Murein hydrolase regulator LrgA homolog. (141 aa)    
Predicted Functional Partners:
lrgB
Antiholin-like protein LrgB; Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses; Belongs to the CidB/LrgB family. LrgB subfamily.
  
 0.996
MCCL_0110
Conserved hypothetical protein; Similar to two-component response regulator.
   
 0.962
MCCL_0296
Conserved hypothetical protein; Similar to effector of murein hydrolase.
  
 0.946
MCCL_0109
Conserved hypothetical protein; Similar to two-component sensor histidine kinase.
 
   
 0.890
MCCL_0295
Conserved hypothetical protein; Similar to murein hydrolase exporter.
  
   
 0.719
MCCL_0113
Conserved hypothetical protein; Similar to ABC transporter permease.
       0.485
MCCL_0114
ABC transporter ATP-binding protein.
       0.476
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
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