Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nreBTwo-component sensor histidine kinase of nitrate reduction operon. (343 aa)    
Predicted Functional Partners:
nreC
Two-component response regulator NreC.
 
 0.998
nreA
Control of nitrate reduction protein NreA.
 
  
 0.907
MCCL_1570
Two-component response regulator.
 
 
 0.862
vraR
Two-component response regulator VraR.
 
 
 0.860
MCCL_0294
Conserved hypothetical protein; Similar to two-component response regulator.
 
 
 0.859
narJ
Respiratory nitrate reductase delta chain.
 
     0.805
MCCL_0293
Conserved hypothetical protein; Similar to sensor histidine kinase.
  
     0.767
narG
Respiratory nitrate reductase alpha chain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
  
 0.750
narH
Respiratory nitrate reductase beta chain.
       0.720
narI
Nitrate reductase gamma chain.
       0.720
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
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