STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lctDL-lactate dehydrogenase 1; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (315 aa)    
Predicted Functional Partners:
pykA
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.973
porA
2-oxoacid ferredoxin oxidoreductase alpha subunit homolog.
  
 
 0.965
MCCL_0071
D-specific D-2-hydroxyacid dehydrogenase homolog; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.944
porB
2-oxoacid ferredoxin oxidoreductase beta subunit.
  
 
 0.926
MCCL_0729
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 0.923
MCCL_0255
Lactate dehydrogenase homolog; Belongs to the LDH/MDH superfamily.
  
  
 
0.921
pdhB
Pyruvate dehydrogenase E1 component beta subunit.
   
 0.919
pflB
Formate acetyltransferase.
   
 
 0.914
ppsA
Phosphoenolpyruvate synthase/pyruvate phosphate dikinase.
  
 
 0.911
pdhA
Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
   
 
 0.910
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
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