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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lutAConserved hypothetical protein; Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. (245 aa)    
Predicted Functional Partners:
lutB
Iron-sulfur cluster binding protein YvfW homolog; Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate.
 
 0.999
lutC
Conserved hypothetical protein; Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.
 
 
 0.989
lctP
L-lactate permease 1; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
 
  
 0.703
MCCL_0383
FAD-dependent pyridine nucleotide-disulphide oxidoreductase homolog; Belongs to the sulfur carrier protein TusA family.
  
 
 0.701
MCCL_0171
Conserved hypothetical protein; Similar to transcriptional regulator, GntR family.
  
  
 0.553
porA
2-oxoacid ferredoxin oxidoreductase alpha subunit homolog.
  
  
 0.532
MCCL_0175
Conserved hypothetical protein; Similar to functionally unknown protein.
       0.516
secDF
Protein translocase membrane protein SecDF subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
  
  
 0.417
narI
Nitrate reductase gamma chain.
  
 
 0.405
pyrK
Dihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
  
  
 0.402
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
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