STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCCL_0348Conserved hypothetical protein; Similar to transcriptional repressor of ribose operon. (322 aa)    
Predicted Functional Partners:
rbsK
Ribokinase homolog; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 0.917
MCCL_0350
Hypothetical protein; Belongs to the RbsD / FucU family.
 
  
 0.892
MCCL_0351
Conserved hypothetical protein; Converts alpha-aldose to the beta-anomer.
 
   
 0.811
pykA
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 
 0.622
ptsH
Phosphocarrier protein HPr.
   
 
 0.564
MCCL_0339
Conserved hypothetical protein; Similar to lactose phosphotransferase system repressor.
  
   
 0.511
MCCL_0374
Conserved hypothetical protein; Similar to fructokinase.
 
  
 0.502
MCCL_1368
Conserved hypothetical protein; Similar to GntR family transcriptional regulator.
  
 
   0.496
fruB
Fructose specific permease.
     
 0.482
ribBA
3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II homolog; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
   0.474
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.