STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metNABC transporter, ATP-binding protein homolog; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (340 aa)    
Predicted Functional Partners:
MCCL_0418
ABC transporter, permease protein homolog.
 
 0.998
MCCL_0419
ABC transporter, substrate-binding protein homolog; Belongs to the nlpA lipoprotein family.
 
 0.997
MCCL_0540
ABC transporter, permease protein.
 
 0.991
MCCL_0254
Conserved hypothetical protein; Similar to ABC transporter substrate-binding protein; Belongs to the nlpA lipoprotein family.
 
 0.987
MCCL_0541
ABC transporter, substrate-binding protein; Belongs to the nlpA lipoprotein family.
 
 0.987
metN-2
ABC transporter, ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
  
  
 
0.905
metAA
Conserved hypothetical protein; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
  
    0.525
MCCL_0096
Iron-dependent repressor homolog.
   
   0.498
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
  
 0.472
MCCL_0416
Conserved hypothetical protein; Similar to phospholipase D endonuclease domain protein.
       0.432
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
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