STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hisCHistidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (350 aa)    
Predicted Functional Partners:
MCCL_0344
Conserved hypothetical protein; Similar to histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily.
  
 
 0.914
MCCL_1508
Conserved hypothetical protein; Similar to menaquinone-specific isochorismate synthase.
 
  
  0.825
MCCL_1210
Conserved hypothetical protein; Similar to functionally unknown protein; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
  
  
 0.819
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
  
 0.706
thrA
Aspartate kinase; Belongs to the aspartokinase family.
 
  
 0.692
cmk
Cytidylate kinase.
 
    0.683
MCCL_0467
Conserved hypothetical protein; Similar to anthranilate/para-aminobenzoate synthases component I.
  
  
 0.677
aroA-2
3-deoxy-D-arabino-heptulosonate 7-phosphate synthase.
  
  
 0.671
MCCL_0476
Conserved hypothetical protein; Similar to 5'(3')-deoxyribonucleotidase.
       0.636
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
  
  
 0.621
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
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