STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCCL_0494Conserved hypothetical protein; Similar to functionally unknown protein. (354 aa)    
Predicted Functional Partners:
MCCL_0492
Conserved hypothetical protein; Similar to functionally unknown protein.
  
    0.778
MCCL_0493
Conserved hypothetical protein; Similar to functionally unknown protein.
       0.777
MCCL_0495
Conserved hypothetical protein; Similar to functionally unknown protein.
       0.756
rsbW
Anti-sigma regulatory factor; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
  
 
 0.680
pepT
Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
       0.558
MCCL_0496
Lipophilic regulator protein homolog.
  
    0.537
secDF
Protein translocase membrane protein SecDF subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
 
    0.528
MCCL_1571
Signal transduction histidine kinase.
 
   
 0.484
rsbU
Sigma B regulation protein RsbU.
  
  
 0.480
MCCL_0977
Conserved hypothetical protein; Similar to ORF002 of bacteriophage 2638A.
  
    0.455
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.