STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCCL_0591ATP-dependent nuclease subunit B; ATP-dependent DNA helicase. (1118 aa)    
Predicted Functional Partners:
MCCL_0592
Conserved hypothetical protein; ATP-dependent DNA helicase.
 
 
 0.999
MCCL_0910
Conserved hypothetical protein; Similar to functionally unknown protein.
  
 
 0.901
MCCL_0593
Hypothetical protein.
       0.773
MCCL_0589
Conserved hypothetical protein; Similar to functionally unknown protein.
 
     0.634
MCCL_0590
type-I signal peptidase SipB homolog; Belongs to the peptidase S26 family.
       0.634
MCCL_1211
Conserved hypothetical protein; Similar to functionally unknown protein.
 
     0.619
MCCL_0594
Fumarylacetoacetate hydrolase family protein.
       0.610
sbcD
Conserved hypothetical protein; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
  
 0.508
MCCL_1273
Conserved hypothetical protein; Similar to single-strand DNA-specific exonuclease.
     
 0.497
MCCL_1257
Conserved hypothetical protein; Similar to functionally unknown protein; Belongs to the UPF0297 family.
  
     0.496
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
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