node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
purC | purD | MCCL_0689 | MCCL_0697 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | 0.992 |
purC | purE | MCCL_0689 | MCCL_0687 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Conserved hypothetical protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.999 |
purC | purF | MCCL_0689 | MCCL_0693 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.994 |
purC | purH | MCCL_0689 | MCCL_0696 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.991 |
purC | purK | MCCL_0689 | MCCL_0688 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Conserved hypothetical protein; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.997 |
purC | purL | MCCL_0689 | MCCL_0692 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthetase PurL; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to ass [...] | 0.989 |
purC | purM | MCCL_0689 | MCCL_0694 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine cyclo-ligase homolog. | 0.994 |
purC | purN | MCCL_0689 | MCCL_0695 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.992 |
purC | purQ | MCCL_0689 | MCCL_0691 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.989 |
purC | purS | MCCL_0689 | MCCL_0690 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Conserved hypothetical protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer [...] | 0.985 |
purD | purC | MCCL_0697 | MCCL_0689 | Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | 0.992 |
purD | purE | MCCL_0697 | MCCL_0687 | Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | Conserved hypothetical protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.999 |
purD | purF | MCCL_0697 | MCCL_0693 | Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.999 |
purD | purH | MCCL_0697 | MCCL_0696 | Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase. | 0.996 |
purD | purK | MCCL_0697 | MCCL_0688 | Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | Conserved hypothetical protein; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.995 |
purD | purL | MCCL_0697 | MCCL_0692 | Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthetase PurL; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to ass [...] | 0.991 |
purD | purM | MCCL_0697 | MCCL_0694 | Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | Phosphoribosylformylglycinamidine cyclo-ligase homolog. | 0.999 |
purD | purN | MCCL_0697 | MCCL_0695 | Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.999 |
purD | purQ | MCCL_0697 | MCCL_0691 | Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.998 |
purD | purS | MCCL_0697 | MCCL_0690 | Phosphoribosylamine-glycine ligase; Belongs to the GARS family. | Conserved hypothetical protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer [...] | 0.985 |