| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MCCL_0590 | MCCL_0789 | MCCL_0590 | MCCL_0789 | type-I signal peptidase SipB homolog; Belongs to the peptidase S26 family. | Type-1 signal peptidase 1B; Belongs to the peptidase S26 family. | 0.903 |
| MCCL_0590 | MCCL_0847 | MCCL_0590 | MCCL_0847 | type-I signal peptidase SipB homolog; Belongs to the peptidase S26 family. | Putative zinc metalloprotease yluc homolog. | 0.494 |
| MCCL_0590 | lepA | MCCL_0590 | MCCL_1236 | type-I signal peptidase SipB homolog; Belongs to the peptidase S26 family. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.630 |
| MCCL_0590 | rnc | MCCL_0590 | MCCL_0817 | type-I signal peptidase SipB homolog; Belongs to the peptidase S26 family. | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.419 |
| MCCL_0590 | rnhB | MCCL_0590 | MCCL_0830 | type-I signal peptidase SipB homolog; Belongs to the peptidase S26 family. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.542 |
| MCCL_0590 | secA | MCCL_0590 | MCCL_0502 | type-I signal peptidase SipB homolog; Belongs to the peptidase S26 family. | Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.418 |
| MCCL_0590 | secDF | MCCL_0590 | MCCL_1276 | type-I signal peptidase SipB homolog; Belongs to the peptidase S26 family. | Protein translocase membrane protein SecDF subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.621 |
| MCCL_0590 | secY | MCCL_0590 | MCCL_0215 | type-I signal peptidase SipB homolog; Belongs to the peptidase S26 family. | Preprotein translocase SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.443 |
| MCCL_0788 | MCCL_0789 | MCCL_0788 | MCCL_0789 | Regulatory protein. | Type-1 signal peptidase 1B; Belongs to the peptidase S26 family. | 0.529 |
| MCCL_0789 | MCCL_0590 | MCCL_0789 | MCCL_0590 | Type-1 signal peptidase 1B; Belongs to the peptidase S26 family. | type-I signal peptidase SipB homolog; Belongs to the peptidase S26 family. | 0.903 |
| MCCL_0789 | MCCL_0788 | MCCL_0789 | MCCL_0788 | Type-1 signal peptidase 1B; Belongs to the peptidase S26 family. | Regulatory protein. | 0.529 |
| MCCL_0789 | MCCL_0847 | MCCL_0789 | MCCL_0847 | Type-1 signal peptidase 1B; Belongs to the peptidase S26 family. | Putative zinc metalloprotease yluc homolog. | 0.494 |
| MCCL_0789 | lepA | MCCL_0789 | MCCL_1236 | Type-1 signal peptidase 1B; Belongs to the peptidase S26 family. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.630 |
| MCCL_0789 | phoB | MCCL_0789 | MCCL_0790 | Type-1 signal peptidase 1B; Belongs to the peptidase S26 family. | Alkaline phosphatase; Belongs to the alkaline phosphatase family. | 0.605 |
| MCCL_0789 | rnc | MCCL_0789 | MCCL_0817 | Type-1 signal peptidase 1B; Belongs to the peptidase S26 family. | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.419 |
| MCCL_0789 | rnhB | MCCL_0789 | MCCL_0830 | Type-1 signal peptidase 1B; Belongs to the peptidase S26 family. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.542 |
| MCCL_0789 | secA | MCCL_0789 | MCCL_0502 | Type-1 signal peptidase 1B; Belongs to the peptidase S26 family. | Preprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.427 |
| MCCL_0789 | secDF | MCCL_0789 | MCCL_1276 | Type-1 signal peptidase 1B; Belongs to the peptidase S26 family. | Protein translocase membrane protein SecDF subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.621 |
| MCCL_0789 | secY | MCCL_0789 | MCCL_0215 | Type-1 signal peptidase 1B; Belongs to the peptidase S26 family. | Preprotein translocase SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.443 |
| MCCL_0847 | MCCL_0590 | MCCL_0847 | MCCL_0590 | Putative zinc metalloprotease yluc homolog. | type-I signal peptidase SipB homolog; Belongs to the peptidase S26 family. | 0.494 |
