STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
recGATP-dependent DNA helicase; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (678 aa)    
Predicted Functional Partners:
sdhA
L-serine deaminase alpha subunit; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
    0.853
sdhB
L-serine dehydratase beta subunit; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
    0.837
MCCL_0812
Conserved hypothetical protein; Similar to sortase.
       0.774
MCCL_1273
Conserved hypothetical protein; Similar to single-strand DNA-specific exonuclease.
 
   
 0.690
MCCL_0808
Conserved hypothetical protein; Similar to functionally unknown protein.
  
    0.679
plsX
Fatty acid/phospholipid synthesis protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
  
  
 0.658
polA
DNA polymerase I homolog; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
   
 0.615
recQ
ATP-dependent DNA helicase RecQ.
   
  
 0.557
MCCL_1238
Conserved hypothetical protein; Similar to DNA internalization-related competence protein ComEC/Rec2.
 
   
 0.549
recX
Conserved hypothetical protein; Modulates RecA activity; Belongs to the RecX family.
 
  
 0.544
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
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