STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sbcDConserved hypothetical protein; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (372 aa)    
Predicted Functional Partners:
MCCL_1003
Conserved hypothetical protein; Similar to exonuclease SbcC.
 
 0.999
polA
DNA polymerase I homolog; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.954
dinG
Conserved hypothetical protein; 3'-5' exonuclease.
  
 0.718
MCCL_1087
Conserved hypothetical protein; Similar to 5'-3' exonuclease.
   
 0.628
MCCL_0377
Conserved hypothetical protein; Similar to ATP-dependent DNA helicase RecQ.
  
 0.619
recQ
ATP-dependent DNA helicase RecQ.
  
 0.610
MCCL_1133
Conserved hypothetical protein; Similar to ATP-dependent DNA helicase recQ.
  
 0.610
recA
Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.609
MCCL_0258
Truncated sulfate permease family protein.
  
   0.597
MCCL_1004
Conserved hypothetical protein; Similar to cytochrome c oxidase Cu(A) center assembly protein.
       0.564
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.