STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proCPyrroline-5-carboxylate reductase homolog; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (267 aa)    
Predicted Functional Partners:
MCCL_1451
Conserved hypothetical protein; Similar to proline dehydrogenase.
   
 0.939
MCCL_0582
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 0.912
MCCL_1151
Conserved hypothetical protein; Similar to short-chain dehydrogenase.
       0.721
MCCL_1238
Conserved hypothetical protein; Similar to DNA internalization-related competence protein ComEC/Rec2.
     
 0.645
MCCL_1455
Conserved hypothetical protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
 
 0.572
guaA
Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.
     
 0.538
rocD
Ornithine aminotransferase; Catalyzes the interconversion of ornithine to glutamate semialdehyde.
  
  
 0.481
pykA
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.462
MCCL_0467
Conserved hypothetical protein; Similar to anthranilate/para-aminobenzoate synthases component I.
     
 0.452
argG
Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
 
   
 0.441
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
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