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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCCL_1211Conserved hypothetical protein; Similar to functionally unknown protein. (229 aa)    
Predicted Functional Partners:
MCCL_1210
Conserved hypothetical protein; Similar to functionally unknown protein; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
  
  
 0.962
MCCL_0820
Conserved hypothetical protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.
  
     0.748
MCCL_1257
Conserved hypothetical protein; Similar to functionally unknown protein; Belongs to the UPF0297 family.
  
     0.740
MCCL_0592
Conserved hypothetical protein; ATP-dependent DNA helicase.
 
     0.656
sigA
RNA polymerase sigma factor SigA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
       0.634
whiA
Conserved hypothetical protein; Involved in cell division and chromosome segregation.
  
     0.632
MCCL_0591
ATP-dependent nuclease subunit B; ATP-dependent DNA helicase.
 
     0.619
dnaG
Conserved hypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
       0.618
MCCL_1212
Conserved hypothetical protein; Similar to cytochrome c550.
       0.617
MCCL_0852
Conserved hypothetical protein; Similar to functionally unknown protein.
  
     0.581
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
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