Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MCCL_1237Conserved hypothetical protein; Similar to DNA polymerase III delta subunit. (275 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III beta chain, sliding clamp subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is requir [...]
 
 
 0.994
dnaE
DNA polymerase III alpha chain.
  
 0.990
dnaX
DNA polymerase III gamma and tau subunits homolog; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 0.987
MCCL_1928
Conserved hypothetical protein; Similar to DNA polymerase III delta subunit.
 
 
 0.983
MCCL_1627
Conserved hypothetical protein; Similar to exonuclease.
    
 0.945
polC
DNA polymerase III PolC-type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
    
 0.938
polA
DNA polymerase I homolog; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
   
 0.719
MCCL_1238
Conserved hypothetical protein; Similar to DNA internalization-related competence protein ComEC/Rec2.
 
   
 0.662
recO
Conserved hypothetical protein; Involved in DNA repair and RecF pathway recombination.
  
   
 0.595
dinG
Conserved hypothetical protein; 3'-5' exonuclease.
     
 0.567
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
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