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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCCL_1240Conserved hypothetical protein; Similar to competence protein comEA. (220 aa)    
Predicted Functional Partners:
MCCL_1238
Conserved hypothetical protein; Similar to DNA internalization-related competence protein ComEC/Rec2.
 
  
 0.918
comEB
Late competence operon required for DNA binding and uptake ComEB.
  
    0.798
nadD
Conserved hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
     0.764
MCCL_1186
Conserved hypothetical protein; Similar to DNA transport machinery protein comGB.
  
  
 0.739
MCCL_1187
Conserved hypothetical protein; Similar to late competence protein comGA.
  
  
 0.729
rsfS
Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
       0.729
MCCL_1243
Conserved hypothetical protein; Similar to functionally unknown protein.
       0.729
MCCL_0499
Conserved hypothetical protein; Similar to comF operon protein 1.
   
  
 0.728
MCCL_1295
Conserved hypothetical protein; Similar to aspartic endopeptidase.
  
  
 0.705
MCCL_1185
Exogenous DNA-binding protein comGC homolog; Required for transformation and DNA binding.
   
  
 0.611
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
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