Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MCCL_1265Conserved hypothetical protein; Similar to ATPase, AAA family. (419 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III beta chain, sliding clamp subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is requir [...]
  
 
 
 0.823
MCCL_1264
Conserved hypothetical protein; Similar to transcriptional regulator.
       0.669
MCCL_0377
Conserved hypothetical protein; Similar to ATP-dependent DNA helicase RecQ.
  
 
 0.634
recQ
ATP-dependent DNA helicase RecQ.
  
 
 0.579
MCCL_1133
Conserved hypothetical protein; Similar to ATP-dependent DNA helicase recQ.
  
 
 0.579
smc
Conserved hypothetical protein; Required for chromosome condensation and partitioning. Belongs to the SMC family.
 
   0.441
recA
Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.424
MCCL_1950
Chromosome partitioning protein ParB homolog; Belongs to the ParB family.
 
  
 0.419
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
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