Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCCL_1295Conserved hypothetical protein; Similar to aspartic endopeptidase. (245 aa)    
Predicted Functional Partners:
MCCL_1186
Conserved hypothetical protein; Similar to DNA transport machinery protein comGB.
 
  
 0.937
MCCL_1187
Conserved hypothetical protein; Similar to late competence protein comGA.
 
 
 0.922
MCCL_1238
Conserved hypothetical protein; Similar to DNA internalization-related competence protein ComEC/Rec2.
 
  
 0.877
MCCL_1294
DNA repair protein RadC homolog; Belongs to the UPF0758 family.
     
 0.865
MCCL_0833
Conserved hypothetical protein; Similar to DNA processing Smf protein.
 
  
 0.826
MCCL_1185
Exogenous DNA-binding protein comGC homolog; Required for transformation and DNA binding.
 
  
 0.816
MCCL_1240
Conserved hypothetical protein; Similar to competence protein comEA.
  
  
 0.801
MCCL_1293
Hypothetical protein.
       0.779
MCCL_0499
Conserved hypothetical protein; Similar to comF operon protein 1.
  
  
 0.677
secDF
Protein translocase membrane protein SecDF subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
     
 0.670
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
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