STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCCL_1316Conserved hypothetical protein; Similar to MarR family transcriptional regulator. (151 aa)    
Predicted Functional Partners:
murI
Conserved hypothetical protein; Provides the (R)-glutamate required for cell wall biosynthesis.
  
    0.743
MCCL_1314
Conserved hypothetical protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
       0.693
MCCL_1313
Conserved hypothetical protein; Similar to functionally unknown protein.
  
    0.690
MCCL_0383
FAD-dependent pyridine nucleotide-disulphide oxidoreductase homolog; Belongs to the sulfur carrier protein TusA family.
  
  
 0.546
MCCL_1845
Conserved hypothetical protein; Similar to functionally unknown protein.
  
     0.538
sdhB-2
Succinate dehydrogenase iron-sulfur protein subunit.
       0.521
sdhA-2
Succinate dehydrogenase flavoprotein subunit.
       0.520
sdhC
Succinate dehydrogenase cytochrome b558 subunit.
       0.462
MCCL_1846
Conserved hypothetical protein; Similar to functionally unknown protein.
  
     0.430
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
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