STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdhMalate dehydrogenase homolog; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (309 aa)    
Predicted Functional Partners:
citZ
Citrate synthase II; Belongs to the citrate synthase family.
  
 0.987
fumC
Fumarate hydratase, class-II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.959
citC
Isocitrate dehydrogenase.
  
 
 0.926
MCCL_0729
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 0.923
pckA
Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
  
 
 0.912
mqo
Malate:quinone oxidoreductase.
    
 0.911
mqo-2
Malate:quinone oxidoreductase.
    
 0.911
MCCL_1646
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.839
argH
Argininosuccinate lyase.
  
 0.830
gudB
NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.827
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.