STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCCL_1415Conserved hypothetical protein; Similar to functionally unknown protein. (167 aa)    
Predicted Functional Partners:
MCCL_1416
Conserved hypothetical protein; Similar to general stress protein.
  
    0.924
MCCL_0489
Conserved hypothetical protein; Similar to functionally unknown protein.
  
    0.696
aroA-2
3-deoxy-D-arabino-heptulosonate 7-phosphate synthase.
       0.604
murC
UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
       0.590
MCCL_1419
phenylalanyl-tRNA synthetase beta subunit homolog; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
    0.573
MCCL_1418
Conserved hypothetical protein; Similar to DNA segregation ATPase FtsK/SpoIIIE family protein; Belongs to the FtsK/SpoIIIE/SftA family.
       0.561
MCCL_1420
Conserved hypothetical protein; Similar to functionally unknown protein.
       0.561
sigA
RNA polymerase sigma factor SigA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
    0.479
rsbW
Anti-sigma regulatory factor; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
  
    0.438
MCCL_0122
GCN5-related N-acetyltransferase homolog.
   
    0.433
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.