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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
murCUDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (431 aa)    
Predicted Functional Partners:
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
 
 0.996
mruD
UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
 
 0.994
ddl
D-alanine-D-alanine ligase; Cell wall formation.
  
 0.971
murE
UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase homolog; Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan; Belongs to the MurCDEF family. MurE subfamily.
  
 0.896
MCCL_1418
Conserved hypothetical protein; Similar to DNA segregation ATPase FtsK/SpoIIIE family protein; Belongs to the FtsK/SpoIIIE/SftA family.
 
  
 0.894
MCCL_1420
Conserved hypothetical protein; Similar to functionally unknown protein.
 
     0.893
mraY
UDP-MurNAc-pentapeptide phosphotransferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
  
 0.875
divIB
Conserved hypothetical protein; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily.
 
  
 0.874
MCCL_1419
phenylalanyl-tRNA synthetase beta subunit homolog; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.868
murZ
UDP-N-acetylglucosamine 1-carboxyvinyltransferase homolog; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
 
  
 0.862
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
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