STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCCL_1429Conserved hypothetical protein; Similar to functionally unknown protein. (263 aa)    
Predicted Functional Partners:
trmB
tRNA (guanine-N(7)-)-methyltransferase homolog; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
    0.852
MCCL_1712
Conserved hypothetical protein; Similar to functionally unknown protein.
  
     0.700
MCCL_1906
Conserved hypothetical protein; Similar to cell-division initiation protein.
  
     0.653
ezrA
Conserved hypothetical protein; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
  
     0.584
MCCL_0618
Conserved hypothetical protein; Similar to functionally unknown protein.
  
     0.571
MCCL_0616
GTP pyrophosphokinase homolog.
  
     0.569
MCCL_1094
Conserved hypothetical protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
  
     0.568
MCCL_1430
Conserved hypothetical protein; Similar to peptidase.
       0.526
MCCL_1427
Conserved hypothetical protein; Similar to aminotransferase.
       0.520
MCCL_1379
Conserved hypothetical protein; Similar to S-adenosyl-L-methionine-dependent methyltransferase.
 
     0.472
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
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