STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCCL_1600Conserved hypothetical protein; Similar to functionally unknown protein. (326 aa)    
Predicted Functional Partners:
MCCL_1420
Conserved hypothetical protein; Similar to functionally unknown protein.
  
     0.758
MCCL_1599
A/G-specific adenine glycosylase homolog; Adenine glycosylase active on G-A mispairs.
       0.713
MCCL_1110
Conserved hypothetical protein; Similar to functionally unknown protein.
  
     0.712
MCCL_1501
Conserved hypothetical protein; Similar to MutT/nudix family protein.
  
     0.704
MCCL_0887
Conserved hypothetical protein; Similar to functionally unknown protein; Belongs to the UPF0342 family.
  
     0.683
MCCL_1416
Conserved hypothetical protein; Similar to general stress protein.
  
     0.652
rsbW
Anti-sigma regulatory factor; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
  
     0.638
pcrB
PcrB family protein; Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond- formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.
  
     0.626
MCCL_0741
Conserved hypothetical protein; Similar to functionally unknown protein; Belongs to the UPF0342 family.
  
     0.613
sigB
Sigma factor B; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
     0.611
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
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