STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vraSTwo-component sensor histidine kinase VraS homolog. (339 aa)    
Predicted Functional Partners:
vraR
Two-component response regulator VraR.
 0.998
MCCL_1616
Conserved hypothetical protein; Similar to functionally unknown protein.
 
    0.974
nreC
Two-component response regulator NreC.
 
 0.870
MCCL_1570
Two-component response regulator.
 
 0.870
MCCL_0294
Conserved hypothetical protein; Similar to two-component response regulator.
 
 
 0.867
MCCL_1617
Hypothetical protein.
       0.658
map
Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
       0.532
MCCL_1372
Conserved hypothetical protein; Similar to functionally unknown protein.
  
     0.529
MCCL_1605
Conserved hypothetical protein; Similar to transglycosylase domain protein.
   
  
 0.484
MCCL_1407
Conserved hypothetical protein; Similar to penicillin-binding protein 1A.
  
    0.468
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.