STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurrence
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Experiments
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[Homology]
Score
MCCL_1649Nicotinic acid phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (485 aa)    
Predicted Functional Partners:
MCCL_1449
Conserved hypothetical protein; Similar to transcriptional regulator.
    
 0.967
nadD
Conserved hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.953
nadE
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family.
 
  
 0.941
deoD
Purine nucleoside phosphorylase homolog.
     
 0.912
MCCL_0552
Conserved hypothetical protein; Similar to functionally unknown protein; Belongs to the 5'-nucleotidase family.
    
  0.905
MCCL_1647
Conserved hypothetical protein; Similar to functionally unknown protein.
  
    0.742
MCCL_1651
Conserved hypothetical protein; Similar to nitric-oxide synthase.
       0.574
MCCL_1650
Conserved hypothetical protein; Similar to transriptional regulator.
       0.572
MCCL_1852
Deoxyadenosine kinase homolog.
   
    0.493
MCCL_1653
Conserved hypothetical protein; Similar to pyrazinamidase/nicotinamidase.
 
  
 0.485
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
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