Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
speESpermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (286 aa)    
Predicted Functional Partners:
speH
S-adenosylmethionine decarboxylase homolog; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
 
 0.999
MCCL_1664
Conserved hypothetical protein; Similar to agmatinase; Belongs to the arginase family.
 
 
 0.990
MCCL_1661
Conserved hypothetical protein; Similar to lysine decarboxylase.
 
 0.975
MCCL_0759
Conserved hypothetical protein; Similar to functionally unknown protein; Belongs to the multicopper oxidase YfiH/RL5 family.
    
  0.901
MCCL_0856
Spermidine acetyltransferase.
    
  0.900
mtnN
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase homolog; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
    
  0.900
MCCL_1665
Conserved hypothetical protein; Similar to functionally unknown protein.
       0.545
MCCL_1572
GCN5-related N-acetyltransferase homolog; Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase homolog.
  
  
 0.534
MCCL_1660
Conserved hypothetical protein; Similar to functionally unknown protein.
       0.469
rimM
16S rRNA processing protein homolog; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.
   
    0.439
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
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