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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
lipLLipoate-protein ligase A homolog; Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes; Belongs to the octanoyltransferase LipL family. (274 aa)    
Predicted Functional Partners:
lipA
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
  
 
 0.946
lipM
Conserved hypothetical protein; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation.
    
 0.927
lplA
Lipoate-protein ligase A.
    
 0.927
MCCL_1833
Phosphotransacetylase.
  
  
 0.890
gcvH
Glycine cleavage system H protein; Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate; Belongs to the GcvH family.
 
 
 0.853
MCCL_0527
Conserved hypothetical protein; Similar to carboxylesterase.
  
     0.731
MCCL_1834
Conserved hypothetical protein; Similar to functionally unknown protein.
 
     0.686
MCCL_1324
Conserved hypothetical protein; Similar to colicin V production protein.
  
    0.684
pdhC
Dihydrolipoamide acetyltransferase subunit E2.
 
 0.666
MCCL_0078
Conserved hypothetical protein; Similar to carboxylesterase.
  
     0.663
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
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