Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cysKCysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (310 aa)    
Predicted Functional Partners:
cysE
Serine acetyltransferase.
 
 0.995
MCCL_1790
Cystathionine gamma-synthase homolog.
  
 0.982
MCCL_1427
Conserved hypothetical protein; Similar to aminotransferase.
    
 0.923
MCCL_0251
Oxidoreductase family protein.
   
 
  0.900
luxS
Autoinducer-2 production protein; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
  
 
 0.898
cysS
cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.885
MCCL_0060
O-acetylhomoserine (thiol)-lyase homolog.
  
 
 0.838
MCCL_1088
Conserved hypothetical protein; Similar to thiosulfate sulfurtransferase.
  
 
 0.834
MCCL_1789
Hypothetical protein.
 
 
0.833
MCCL_0330
Conserved hypothetical protein; Similar to homocysteine S-methyltransferase.
     
 0.808
Your Current Organism:
Macrococcus caseolyticus
NCBI taxonomy Id: 458233
Other names: M. caseolyticus JCSC5402, Macrococcus caseolyticus JCSC5402, Macrococcus caseolyticus str. JCSC5402, Macrococcus caseolyticus strain JCSC5402
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.