node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Shal_0428 | Shal_1220 | Shal_0428 | Shal_1220 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: shm:Shewmr7_1184 MazG family protein. | 0.912 |
Shal_0428 | Shal_1551 | Shal_0428 | Shal_1551 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | PFAM: protein of unknown function DUF479; KEGG: slo:Shew_2339 protein of unknown function DUF479. | 0.900 |
Shal_0428 | Shal_1732 | Shal_0428 | Shal_1732 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | KEGG: pin:Ping_0683 cystathionine beta-lyase; TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. | 0.828 |
Shal_0428 | Shal_1937 | Shal_0428 | Shal_1937 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: sbm:Shew185_2117 pyridoxal-5'-phosphate-dependent protein beta subunit. | 0.820 |
Shal_0428 | Shal_2581 | Shal_0428 | Shal_2581 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: slo:Shew_2382 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.820 |
Shal_0428 | Shal_3743 | Shal_0428 | Shal_3743 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: ilo:IL2163 cysteine synthase. | 0.820 |
Shal_0428 | coaA | Shal_0428 | Shal_4149 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | TIGRFAM: pantothenate kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: slo:Shew_0143 pantothenate kinase. | 0.926 |
Shal_0428 | coaD | Shal_0428 | Shal_0135 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.954 |
Shal_0428 | dut | Shal_0428 | Shal_0427 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.983 |
Shal_0428 | panC | Shal_0428 | Shal_0749 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.889 |
Shal_1220 | Shal_0428 | Shal_1220 | Shal_0428 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: shm:Shewmr7_1184 MazG family protein. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.912 |
Shal_1220 | Shal_1551 | Shal_1220 | Shal_1551 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: shm:Shewmr7_1184 MazG family protein. | PFAM: protein of unknown function DUF479; KEGG: slo:Shew_2339 protein of unknown function DUF479. | 0.900 |
Shal_1220 | coaA | Shal_1220 | Shal_4149 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: shm:Shewmr7_1184 MazG family protein. | TIGRFAM: pantothenate kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: slo:Shew_0143 pantothenate kinase. | 0.900 |
Shal_1551 | Shal_0428 | Shal_1551 | Shal_0428 | PFAM: protein of unknown function DUF479; KEGG: slo:Shew_2339 protein of unknown function DUF479. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.900 |
Shal_1551 | Shal_1220 | Shal_1551 | Shal_1220 | PFAM: protein of unknown function DUF479; KEGG: slo:Shew_2339 protein of unknown function DUF479. | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: shm:Shewmr7_1184 MazG family protein. | 0.900 |
Shal_1551 | coaA | Shal_1551 | Shal_4149 | PFAM: protein of unknown function DUF479; KEGG: slo:Shew_2339 protein of unknown function DUF479. | TIGRFAM: pantothenate kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: slo:Shew_0143 pantothenate kinase. | 0.908 |
Shal_1551 | coaD | Shal_1551 | Shal_0135 | PFAM: protein of unknown function DUF479; KEGG: slo:Shew_2339 protein of unknown function DUF479. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.904 |
Shal_1732 | Shal_0428 | Shal_1732 | Shal_0428 | KEGG: pin:Ping_0683 cystathionine beta-lyase; TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.828 |
Shal_1732 | Shal_1937 | Shal_1732 | Shal_1937 | KEGG: pin:Ping_0683 cystathionine beta-lyase; TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. | PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: sbm:Shew185_2117 pyridoxal-5'-phosphate-dependent protein beta subunit. | 0.969 |
Shal_1732 | Shal_2581 | Shal_1732 | Shal_2581 | KEGG: pin:Ping_0683 cystathionine beta-lyase; TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. | TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: slo:Shew_2382 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.975 |