STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Shal_1533Transcriptional regulator, TyrR; PFAM: sigma-54 factor interaction domain-containing protein; amino acid-binding ACT domain protein; SMART: PAS domain containing protein; AAA ATPase; KEGG: slo:Shew_1437 transcriptional regulator, TyrR. (515 aa)    
Predicted Functional Partners:
Shal_3705
RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   
 0.775
Shal_2904
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: slo:Shew_2572 enoyl-CoA hydratase/isomerase.
   
    0.664
Shal_1532
PFAM: transcriptional coactivator/pterin dehydratase; KEGG: slo:Shew_1436 transcriptional coactivator/pterin dehydratase.
 
   
 0.639
Shal_1531
KEGG: shw:Sputw3181_2715 phenylalanine-4-hydroxylase; TIGRFAM: phenylalanine-4-hydroxylase; PFAM: aromatic amino acid hydroxylase.
     
 0.521
Shal_1534
PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: sbm:Shew185_1482 fumarylacetoacetate (FAA) hydrolase.
     
 0.515
Shal_2752
PFAM: conserved hypothetical protein; KEGG: shm:Shewmr7_2546 conserved hypothetical protein 1620.
     
 0.440
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.436
Shal_1535
TIGRFAM: maleylacetoacetate isomerase; PFAM: Glutathione S-transferase domain; KEGG: shm:Shewmr7_2670 maleylacetoacetate isomerase.
     
 0.418
Shal_1107
TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: sbm:Shew185_1264 chorismate mutase.
      
 0.412
Shal_2753
PFAM: protein of unknown function DUF463 YcjX family protein; KEGG: slo:Shew_2493 protein of unknown function DUF463, YcjX family protein.
  
  
 0.401
Your Current Organism:
Shewanella halifaxensis
NCBI taxonomy Id: 458817
Other names: S. halifaxensis HAW-EB4, Shewanella halifaxensis HAW-EB4, Shewanella halifaxensis str. HAW-EB4, Shewanella halifaxensis strain HAW-EB4
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