| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Shal_0641 | Shal_2001 | Shal_0641 | Shal_2001 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rpc:RPC_0704 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | PFAM: UvrD/REP helicase; DNA topoisomerase type IA zn finger domain protein; KEGG: sfr:Sfri_0452 UvrD/REP helicase. | 0.861 |
| Shal_0641 | leuS | Shal_0641 | Shal_3228 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rpc:RPC_0704 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | TIGRFAM: leucyl-tRNA synthetase; KEGG: slo:Shew_2929 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.758 |
| Shal_0641 | polA | Shal_0641 | Shal_4220 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rpc:RPC_0704 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.435 |
| Shal_0641 | recA | Shal_0641 | Shal_1232 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rpc:RPC_0704 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.691 |
| Shal_0641 | rpoB | Shal_0641 | Shal_4141 | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rpc:RPC_0704 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.665 |
| Shal_2001 | Shal_0641 | Shal_2001 | Shal_0641 | PFAM: UvrD/REP helicase; DNA topoisomerase type IA zn finger domain protein; KEGG: sfr:Sfri_0452 UvrD/REP helicase. | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rpc:RPC_0704 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | 0.861 |
| Shal_2001 | leuS | Shal_2001 | Shal_3228 | PFAM: UvrD/REP helicase; DNA topoisomerase type IA zn finger domain protein; KEGG: sfr:Sfri_0452 UvrD/REP helicase. | TIGRFAM: leucyl-tRNA synthetase; KEGG: slo:Shew_2929 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.651 |
| Shal_2001 | pheT | Shal_2001 | Shal_1813 | PFAM: UvrD/REP helicase; DNA topoisomerase type IA zn finger domain protein; KEGG: sfr:Sfri_0452 UvrD/REP helicase. | KEGG: slo:Shew_2215 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit. | 0.667 |
| Shal_2001 | polA | Shal_2001 | Shal_4220 | PFAM: UvrD/REP helicase; DNA topoisomerase type IA zn finger domain protein; KEGG: sfr:Sfri_0452 UvrD/REP helicase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.681 |
| Shal_2001 | purL | Shal_2001 | Shal_1380 | PFAM: UvrD/REP helicase; DNA topoisomerase type IA zn finger domain protein; KEGG: sfr:Sfri_0452 UvrD/REP helicase. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.601 |
| Shal_2001 | recA | Shal_2001 | Shal_1232 | PFAM: UvrD/REP helicase; DNA topoisomerase type IA zn finger domain protein; KEGG: sfr:Sfri_0452 UvrD/REP helicase. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.605 |
| Shal_2001 | recC | Shal_2001 | Shal_1857 | PFAM: UvrD/REP helicase; DNA topoisomerase type IA zn finger domain protein; KEGG: sfr:Sfri_0452 UvrD/REP helicase. | Exodeoxyribonuclease V, gamma subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...] | 0.840 |
| Shal_2001 | recD | Shal_2001 | Shal_1855 | PFAM: UvrD/REP helicase; DNA topoisomerase type IA zn finger domain protein; KEGG: sfr:Sfri_0452 UvrD/REP helicase. | Exodeoxyribonuclease V, alpha subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and r [...] | 0.870 |
| Shal_2001 | rpoB | Shal_2001 | Shal_4141 | PFAM: UvrD/REP helicase; DNA topoisomerase type IA zn finger domain protein; KEGG: sfr:Sfri_0452 UvrD/REP helicase. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.704 |
| Shal_2001 | rpoC | Shal_2001 | Shal_4140 | PFAM: UvrD/REP helicase; DNA topoisomerase type IA zn finger domain protein; KEGG: sfr:Sfri_0452 UvrD/REP helicase. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.613 |
| leuS | Shal_0641 | Shal_3228 | Shal_0641 | TIGRFAM: leucyl-tRNA synthetase; KEGG: slo:Shew_2929 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rpc:RPC_0704 pyruvate flavodoxin/ferredoxin oxidoreductase-like. | 0.758 |
| leuS | Shal_2001 | Shal_3228 | Shal_2001 | TIGRFAM: leucyl-tRNA synthetase; KEGG: slo:Shew_2929 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | PFAM: UvrD/REP helicase; DNA topoisomerase type IA zn finger domain protein; KEGG: sfr:Sfri_0452 UvrD/REP helicase. | 0.651 |
| leuS | pheT | Shal_3228 | Shal_1813 | TIGRFAM: leucyl-tRNA synthetase; KEGG: slo:Shew_2929 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | KEGG: slo:Shew_2215 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit. | 0.948 |
| leuS | polA | Shal_3228 | Shal_4220 | TIGRFAM: leucyl-tRNA synthetase; KEGG: slo:Shew_2929 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.588 |
| leuS | purL | Shal_3228 | Shal_1380 | TIGRFAM: leucyl-tRNA synthetase; KEGG: slo:Shew_2929 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.401 |